个人简历
1983年 出生于河北省承德围场
2000-2003 河北省围场县第一中学（高中）
2003-2007 厦门大学化学系（本科）
2007-2013 中国科学院化学研究所胶体界面实验室攻读博士学位
2013年5月10日 博士学问论文答辩
2013.07-2016.02 中国科学院化学研究所，助理研究员
2016.03-2018.10 中国科学院化学研究所，副研究员
2018.11-至今 中国科学院大气物理研究所
发表论文
Emitting/Sensitizing Ions Spatially Separated Lanthanide Nanocrystals for Visualizing Tumors Simultaneously through Up- and Down-conversion Near-infrared II Luminescence in Vivo
Yingying Li‡, Peisen Zhang‡, Haoran Ning, Jianfeng Zeng, Yi Hou, Lihong Jing, Chunyan Liu, Mingyuan Gao*
Small, 2019, just accepted.
Timely Visualization of the Collaterals Formed during Acute Ischemic Stroke with Fe3O4 Nanoparticle-based MR Imaging Probe
Ting Wang, Yi Hou, Bo Bu, Wenxin Wang, Tiancong Ma, Chunyan Liu, Lan Lin, Lin Ma, Xin Lou,* and Mingyuan Gao
Small, 2018, 14, 1800573.
Molecular Mechanisms for Delicately Tuning the Morphology and Property of Fe3O4 Nanoparticle Clusters
Xiaojun Wei, Lihong Jing, Chuanyan Liu, Yi Hou, Mingxia Jiao, and Mingyuan Gao*
CrystEngComm, 2018, just accepted.
A Novel Histochemical Staining Approach for Rare-Earth Based Nanoprobes
Jiayi Huang, Yi Hou*, Tiancong Ma, Peisen Zhang, Yingying Li, Chunyan Liu, Boyuan Zhang, Shanshan Qiu, Jianfeng Zeng, and Mingyuan Gao*
Adv. Therap., 2018, just accepted.
Recent Advancements in Biocompatible Inorganic Nanoparticles towards Biomedical Applications
Mingxia, Jiao, Peisen Zhang, Junli Meng, Yingying Li, Chunyan Liu*, Xiliang Luo, and Mingyuan Gao*
Biomaterials Sci, 2018, DOI: 10.1039/C7BM01020F.
Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in vivo
Tiancong Ma‡, Yi Hou‡, Jianfeng Zeng‡, Chunyan Liu, Peisen Zhang, Lihong Jing, Dihua Shangguan, and Mingyuan Gao*
J. Am. Chem. Soc., 2018, 140(1), 211–218.
The Yin and Yang of Coordinating Co-Solvents in the Size-Tuning of Fe3O4 Nanocrystals through Flow Synthesis
Mingxia Jiao, Lihong Jing, Xiaojun Wei, Chunyan Liu, Xiliang Luo* and Mingyuan Gao*
Nanoscale, 2017, 9(47), 18609-18612.
Tumor Microenvironment-Triggered Aggregation of Anti-Phagocytosis 99mTc-Labelled Fe3O4 Nanoprobes for Enhanced Tumor Imaging in Vivo
Zhenyu Gao‡, Yi Hou‡, Jianfeng Zeng, Lei Chen, Chunyan Liu, Wensheng Yang*, and Mingyuan Gao*
Adv. Mater., 2017, 29(24), 1701095
Differently Sized Magnetic/Upconversion Luminescent NaGdF4:Yb,Er Nanocrystals: Flow Synthesis and Solvent Effects
Mingxia Jiao, Lihong Jing, Chunyan Liu, Yi Hou, Jiayi Huang, Xiaojun Wei, and Mingyuan Gao*
Chem. Commun., 2016, 52(34), 5872-5875.
Detection of Early Primary Colorectal Cancer with Upconversion Luminescence NPs‐Based Molecular Probes
Chunyan Liu‡, Yifei Qi‡, Ruirui Qiao, Yi hou, Kaying Chan, Ziqian Li, Jiayi Huang, Lihong Jing, Jun Du*, and Mingyuan Gao*
Nanoscale, 2016, 8(48), 12579-12587.
Chemical Spacer Design for Engineering the Relaxometric Properties of Core-Shell Structured Rare Earth Nanoparticles
Jiayi Huang, Yi Hou, Chunyan Liu*, Lihong Jing, Tiancong Ma, Xiaodan Sun, and Mingyuan Gao*
Chem. Mater., 2015, 27(23), 7918-7925.
Aqueous Synthesis of PEGylated Copper Sulfide Nanoparticles for Photoacoustic Imaging of Tumors
Ke Ding, Jianfeng Zeng, Lihong Jing, Ruirui Qiao*, Chunyan Liu, Mingxia Jiao, Zhen Li, and Mingyuan Gao*
Nanoscale, 2015, 7(25), 11075-11081.
Protease-Activated Ratiometric Fluorescent Probe for pH Mapping of Malignant Tumors
Yi Hou, Jin Zhou, Zhenyu Gao, Xiaoyu Sun, Chunyan Liu, Dihua Shangguan, Wensheng Yang, and Mingyuan Gao*
ACS Nano, 2015, DOI: 10.1021/acsnano.5b00276.
Flow Synthesis of Biocompatible Fe3O4 Nanoparticles: Insight into the Effects of Residence Time, Fluid Velocity, and Tube Reactor Dimension on Particle Size Distribution
Mingxia Jiao, Jianfeng Zeng, Lihong Jing, Chunyan Liu, and Mingyuan Gao*
Chem. Mater., 2015, 27(4), 1299–1305.
Ultrasensitive in Vivo Detection of Primary Gastric Tumor and Lymphatic Metastasis Using Upconversion Nanoparticles
Ruirui Qiao, Changhao Liu, Muhan Liu, Hao Hu, Chunyan Liu, Yi Hou, Kaichun Wu*, Yenan Lin, Jimin Liang, Mingyuan Gao*
ACS Nano, 2015, 9(2), 2120–2129.
Upconversion Luminescence Nanoparticles-Based Lateral Flow Immunochromatographic Assay for Cephalexin Detection
Chunyan Liu, Wei Ma, Zhenyu Gao, Jiayi Huang, Yi Hou, Chuanlai Xu, Wensheng Yang, and Mingyuan Gao*
J. Mater. Chem. C, 2014, 2(45), 9637-9642.
Restructuring and Remodeling of NaREF4 Nanocrystals by Electron Irradiation
Xiaoyu Sun‡, Bingru Wang‡, Ivan M. Kempson‡, Chunyan Liu, Yi Hou,* and Mingyuan Gao*
Small, 2014, 10(22), 4711-4717.
Are Rare-Earth Nanoparticles Suitable for In Vivo Applications?
Chunyan Liu, Yi Hou, and Mingyuan Gao*
Adv. Mater., 2014, 26(40), 6922-6932.
Anchoring Group Effects of Surface Ligand on Magnetic Properties of Fe3O4 Nanoparticles: Towards High Performance MRI Contrast Agents
Jianfeng Zeng, Lihong Jing, Yi Hou, Mingxia Jiao, Ruirui Qiao, Qiaojuan Jia, Chunyan Liu, Fang Fang, Hao Lei, and Mingyuan Gao*
Adv. Mater., 2014, 26(17), 2694-2698.
Magnetically Engineered Cd-Free Quantum Dots as Dual-modality Probes for Fluorescence/Magnetic Resonance Imaging of Tumors
Ke Ding, Lihong Jing*, Chunyan Liu, Yi Hou, and Mingyuan Gao*
Biomaterials, 2014, 35(5), 1608-1617.
Magnetic/Upconversion Fluorescent NaGdF4:Yb,Er Nanoparticle-Based Dual-Modal Molecular Probes for Imaging Tiny Tumors in Vivo
Chunyan Liu, Zhenyu Gao, Jianfeng Zeng, Yi Hou,* Fang Fang, Yilin Li, Ruirui Qiao, Lin Shen, Hao Lei, Wensheng Yang, and Mingyuan Gao*
ACS Nano, 2013, 7(8), 7227-7240.
NaGdF4 Nanoparticle-Based Molecular Probes for Magnetic Resonance Imaging of Intraperitoneal Tumor Xenografts In Vivo
Yi Hou, Ruirui Qiao, Fang Fang, Xuxia Wang, Chengyan Dong, Kan Liu, Chunyan Liu, Zhaofei Liu, Hao Lei*, Fan Wang, and Mingyuan Gao*
ACS Nano, 2013, 7(1), 330-338.
Lateral Flow Immunochromatographic Assay for Sensitive Pesticide Detection by Using Fe3O4 Nanoparticle Aggregates as Color Reagents
Chunyan Liu, Qiaojuan Jia, Chunhui Yang, Ruirui Qiao, Lihong Jing, Libing Wang*, Chuanlai Xu, and Mingyuan Gao*
Anal. Chem., 2011, 83(17), 6778-6784.
Rapid and Sensitive Detection of Microcystin by Immunosensor Based on Nuclear Magnetic Resonance
Wei Ma, Wei Chen, Ruirui Qiao, Chunyan Liu, Chunhui Yang, Zhuokun Li, Dinghua Xu,Chifang Peng, Zhengyu Jin, Chuanlai Xu*, Shuifang Zhu, LibingWang*
Biosensors and Bioelectronics, 2009, 25(1), 240–243.
申请专利
一种基于上转换荧光/磁性纳米颗粒的免疫层析试纸及其制备方法
高明远，刘春艳，侯毅
中国发明专利申请（201310124432.9）
申请日期：2013年4月11日
全部服务领域
个人简历
1983年 出生于河北省承德围场
2000-2003 河北省围场县第一中学（高中）
2003-2007 厦门大学化学系（本科）
2007-2013 中国科学院化学研究所胶体界面实验室攻读博士学位
2013年5月10日 博士学问论文答辩
2013.07-2016.02 中国科学院化学研究所，助理研究员
2016.03-2018.10 中国科学院化学研究所，副研究员
2018.11-至今 中国科学院大气物理研究所
发表论文
Emitting/Sensitizing Ions Spatially Separated Lanthanide Nanocrystals for Visualizing Tumors Simultaneously through Up- and Down-conversion Near-infrared II Luminescence in Vivo
Yingying Li‡, Peisen Zhang‡, Haoran Ning, Jianfeng Zeng, Yi Hou, Lihong Jing, Chunyan Liu, Mingyuan Gao*
Small, 2019, just accepted.
Timely Visualization of the Collaterals Formed during Acute Ischemic Stroke with Fe3O4 Nanoparticle-based MR Imaging Probe
Ting Wang, Yi Hou, Bo Bu, Wenxin Wang, Tiancong Ma, Chunyan Liu, Lan Lin, Lin Ma, Xin Lou,* and Mingyuan Gao
Small, 2018, 14, 1800573.
Molecular Mechanisms for Delicately Tuning the Morphology and Property of Fe3O4 Nanoparticle Clusters
Xiaojun Wei, Lihong Jing, Chuanyan Liu, Yi Hou, Mingxia Jiao, and Mingyuan Gao*
CrystEngComm, 2018, just accepted.
A Novel Histochemical Staining Approach for Rare-Earth Based Nanoprobes
Jiayi Huang, Yi Hou*, Tiancong Ma, Peisen Zhang, Yingying Li, Chunyan Liu, Boyuan Zhang, Shanshan Qiu, Jianfeng Zeng, and Mingyuan Gao*
Adv. Therap., 2018, just accepted.
Recent Advancements in Biocompatible Inorganic Nanoparticles towards Biomedical Applications
Mingxia, Jiao, Peisen Zhang, Junli Meng, Yingying Li, Chunyan Liu*, Xiliang Luo, and Mingyuan Gao*
Biomaterials Sci, 2018, DOI: 10.1039/C7BM01020F.
Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in vivo
Tiancong Ma‡, Yi Hou‡, Jianfeng Zeng‡, Chunyan Liu, Peisen Zhang, Lihong Jing, Dihua Shangguan, and Mingyuan Gao*
J. Am. Chem. Soc., 2018, 140(1), 211–218.
The Yin and Yang of Coordinating Co-Solvents in the Size-Tuning of Fe3O4 Nanocrystals through Flow Synthesis
Mingxia Jiao, Lihong Jing, Xiaojun Wei, Chunyan Liu, Xiliang Luo* and Mingyuan Gao*
Nanoscale, 2017, 9(47), 18609-18612.
Tumor Microenvironment-Triggered Aggregation of Anti-Phagocytosis 99mTc-Labelled Fe3O4 Nanoprobes for Enhanced Tumor Imaging in Vivo
Zhenyu Gao‡, Yi Hou‡, Jianfeng Zeng, Lei Chen, Chunyan Liu, Wensheng Yang*, and Mingyuan Gao*
Adv. Mater., 2017, 29(24), 1701095
Differently Sized Magnetic/Upconversion Luminescent NaGdF4:Yb,Er Nanocrystals: Flow Synthesis and Solvent Effects
Mingxia Jiao, Lihong Jing, Chunyan Liu, Yi Hou, Jiayi Huang, Xiaojun Wei, and Mingyuan Gao*
Chem. Commun., 2016, 52(34), 5872-5875.
Detection of Early Primary Colorectal Cancer with Upconversion Luminescence NPs‐Based Molecular Probes
Chunyan Liu‡, Yifei Qi‡, Ruirui Qiao, Yi hou, Kaying Chan, Ziqian Li, Jiayi Huang, Lihong Jing, Jun Du*, and Mingyuan Gao*
Nanoscale, 2016, 8(48), 12579-12587.
Chemical Spacer Design for Engineering the Relaxometric Properties of Core-Shell Structured Rare Earth Nanoparticles
Jiayi Huang, Yi Hou, Chunyan Liu*, Lihong Jing, Tiancong Ma, Xiaodan Sun, and Mingyuan Gao*
Chem. Mater., 2015, 27(23), 7918-7925.
Aqueous Synthesis of PEGylated Copper Sulfide Nanoparticles for Photoacoustic Imaging of Tumors
Ke Ding, Jianfeng Zeng, Lihong Jing, Ruirui Qiao*, Chunyan Liu, Mingxia Jiao, Zhen Li, and Mingyuan Gao*
Nanoscale, 2015, 7(25), 11075-11081.
Protease-Activated Ratiometric Fluorescent Probe for pH Mapping of Malignant Tumors
Yi Hou, Jin Zhou, Zhenyu Gao, Xiaoyu Sun, Chunyan Liu, Dihua Shangguan, Wensheng Yang, and Mingyuan Gao*
ACS Nano, 2015, DOI: 10.1021/acsnano.5b00276.
Flow Synthesis of Biocompatible Fe3O4 Nanoparticles: Insight into the Effects of Residence Time, Fluid Velocity, and Tube Reactor Dimension on Particle Size Distribution
Mingxia Jiao, Jianfeng Zeng, Lihong Jing, Chunyan Liu, and Mingyuan Gao*
Chem. Mater., 2015, 27(4), 1299–1305.
Ultrasensitive in Vivo Detection of Primary Gastric Tumor and Lymphatic Metastasis Using Upconversion Nanoparticles
Ruirui Qiao, Changhao Liu, Muhan Liu, Hao Hu, Chunyan Liu, Yi Hou, Kaichun Wu*, Yenan Lin, Jimin Liang, Mingyuan Gao*
ACS Nano, 2015, 9(2), 2120–2129.
Upconversion Luminescence Nanoparticles-Based Lateral Flow Immunochromatographic Assay for Cephalexin Detection
Chunyan Liu, Wei Ma, Zhenyu Gao, Jiayi Huang, Yi Hou, Chuanlai Xu, Wensheng Yang, and Mingyuan Gao*
J. Mater. Chem. C, 2014, 2(45), 9637-9642.
Restructuring and Remodeling of NaREF4 Nanocrystals by Electron Irradiation
Xiaoyu Sun‡, Bingru Wang‡, Ivan M. Kempson‡, Chunyan Liu, Yi Hou,* and Mingyuan Gao*
Small, 2014, 10(22), 4711-4717.
Are Rare-Earth Nanoparticles Suitable for In Vivo Applications?
Chunyan Liu, Yi Hou, and Mingyuan Gao*
Adv. Mater., 2014, 26(40), 6922-6932.
Anchoring Group Effects of Surface Ligand on Magnetic Properties of Fe3O4 Nanoparticles: Towards High Performance MRI Contrast Agents
Jianfeng Zeng, Lihong Jing, Yi Hou, Mingxia Jiao, Ruirui Qiao, Qiaojuan Jia, Chunyan Liu, Fang Fang, Hao Lei, and Mingyuan Gao*
Adv. Mater., 2014, 26(17), 2694-2698.
Magnetically Engineered Cd-Free Quantum Dots as Dual-modality Probes for Fluorescence/Magnetic Resonance Imaging of Tumors
Ke Ding, Lihong Jing*, Chunyan Liu, Yi Hou, and Mingyuan Gao*
Biomaterials, 2014, 35(5), 1608-1617.
Magnetic/Upconversion Fluorescent NaGdF4:Yb,Er Nanoparticle-Based Dual-Modal Molecular Probes for Imaging Tiny Tumors in Vivo
Chunyan Liu, Zhenyu Gao, Jianfeng Zeng, Yi Hou,* Fang Fang, Yilin Li, Ruirui Qiao, Lin Shen, Hao Lei, Wensheng Yang, and Mingyuan Gao*
ACS Nano, 2013, 7(8), 7227-7240.
NaGdF4 Nanoparticle-Based Molecular Probes for Magnetic Resonance Imaging of Intraperitoneal Tumor Xenografts In Vivo
Yi Hou, Ruirui Qiao, Fang Fang, Xuxia Wang, Chengyan Dong, Kan Liu, Chunyan Liu, Zhaofei Liu, Hao Lei*, Fan Wang, and Mingyuan Gao*
ACS Nano, 2013, 7(1), 330-338.
Lateral Flow Immunochromatographic Assay for Sensitive Pesticide Detection by Using Fe3O4 Nanoparticle Aggregates as Color Reagents
Chunyan Liu, Qiaojuan Jia, Chunhui Yang, Ruirui Qiao, Lihong Jing, Libing Wang*, Chuanlai Xu, and Mingyuan Gao*
Anal. Chem., 2011, 83(17), 6778-6784.
Rapid and Sensitive Detection of Microcystin by Immunosensor Based on Nuclear Magnetic Resonance
Wei Ma, Wei Chen, Ruirui Qiao, Chunyan Liu, Chunhui Yang, Zhuokun Li, Dinghua Xu,Chifang Peng, Zhengyu Jin, Chuanlai Xu*, Shuifang Zhu, LibingWang*
Biosensors and Bioelectronics, 2009, 25(1), 240–243.
申请专利
一种基于上转换荧光/磁性纳米颗粒的免疫层析试纸及其制备方法
高明远，刘春艳，侯毅
中国发明专利申请（201310124432.9）
申请日期：2013年4月11日
